In episode 629, Jamie and James invite Karenn Chan to the podcast for the first time. We go over the evidence for the very important topic of if and when to stop medications for dementia. We’ll give you all the numbers you need to have informed conversations with patients and caregivers of people with dementia. Have a listen and hopefully you will find the discussion useful.

Show Notes
Tools For Practice
Deprescribing Cholinesterase Inhibitors: Good or bad idea?

In episode 628, Jamie and James invite Jennifer Young back to the podcast to talk about the very important topic of sleep and what to use instead of medications. We go over all the evidence for cognitive behavioural therapy for insomnia and the numbers look pretty impressive. Have a listen and hopefully you will be impressed by the benefit.

Show Notes
1) Tools For Practice
Enough Evidence to Put One to Sleep: Cognitive behavioural therapy for insomnia
2) Great Insomnia Website
Sleepwell

In episode 627, Tina and James again invite Danielle Perry and Caitlin Finley back to the podcast to answer the question, in children with peanut allergy, does oral immunotherapy increase peanut tolerance, and what are the adverse effects? It does work, but it is not a cure, so you need to know the numbers and the important context – you’ll get this from this podcast.

Show Notes
Tools For Practice
A Tough Nut to Crack: Does oral immunotherapy improve outcomes in peanut allergy?

In episode 626, Tina and James invite Caitlin Finley and Danielle Perry to the podcast to discuss the evidence for using hydrocortisone or pimecrolimus for atopic dermatitis in patients under the age of 2. They do work, so check out the podcast for all the numbers and the important context.

Show Notes
Tools For Practice
Itchy Beginnings: Can we calm infant eczema?

In episode 625, Mike K and James invite Danielle Perry and Tony Nickonchuk to the podcast to talk about the evidence around blood pressure measurement techniques. You might be surprised by what does and does not influence blood pressure measurements. Check out the podcast.

Show Notes
Tools For Practice
Blood Pressure Measurement Technique: Meaningful mistakes or minor details?

In episode 624, James and Mike K invite Tony Nickonchuk to go over all the new evidence we have for the PCSK9 inhibitors. First, we discuss whether or not the evidence addresses the issue of primary versus secondary prevention. We then give you all the numbers and the context you need to allow you to discuss these with your patients.

Show Notes
Tools For Practice
PCSK9 Inhibitors: Cardiovascular prevention panacea or pricey pokes?

PEIP Conference Oct 16-17, 2026

In episode 623, Jamie and James invite Samantha Moe back again to talk about the never-ending debate as to what is the target for systolic blood pressure. We look at the evidence and then try to put it into a reasonable context because at best the evidence is always nuanced. But at least you will now know the numbers.

Show Notes
Tools For Practice
Less than 140, 130, or 120? Counting down to the optimal systolic blood pressure target.

In episode 622, Jamie and James invite Émélie Braschi back again to talk about if we should be using inhalers that combine corticosteroids and beta-agonists as rescue inhalers. We go over the best available evidence and then try to put the findings into context.

Show Notes
Tools For Practice
Bronchodilator with Benefits? Budesonide-formoterol rescue inhaler for asthma

In episode 621, Tina, James and Mike K talk about the evidence around whole-body MRIs. We discuss how many abnormalities are found, how many cancers are actually found, and finally the lost opportunity costs. You need to know these numbers to talk to your patients about the value or lack thereof of doing this test.

Show Notes
Tools For Practice
Whole-Body MRI for Cancer Screening: Many findings, little benefit update 

MEME conference May8/9 2026 in Vancouver

In episode 620, Mike K and James bring back Danielle Perry, this time to talk about the evidence around the use of colchicine for secondary cardiovascular prevention. There are some large RCTs so we talk about all the numbers and as always put them into the proper context.

Show Notes
Tools For Practice
Back on the stand: Colchicine for secondary cardiovascular prevention update

MEME conference May8/9 2026 in Vancouver