Episode 273: Osteoarthritis treatments - an inflammatory discussion about the evidence – PART II

In episode 273, Mike and James break down even more evidence around treatments for osteoarthritis. In this episode, we discuss topical NSAIDs, alternative therapies, narcotics and conclude, as in the previous podcast, that it is ultimately up to the patient to try to figure out what works best for them.

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Episode 272: Osteoarthritis treatments - an inflammatory discussion about the evidence

In episode 272, Mike and James break down all the evidence around treatments for osteoarthritis. In this episode, we discuss activity, acetaminophen, NSAIDs and the benefits and harms around these treatments and at the end we come to the conclusion that it is ultimately up to the patient to try to figure out what works best for them.

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Episode 271: PREMIUM – DESCARTES, OSLER, ODYSSEY and what you need to know

In episode 271, James and Mike discuss the most recent evidence for two new monoclonal antibody medications that lower lipids. We discuss the two new studies OSLER and ODYSSEY. At the end we both agree that it is great these studies looked at cardiovascular events and at least they are going in the right direction. However, we still have a long way to go before we would consider using them. Read more »

Episode 270: Antivirals for the flu – something to sneeze about

In episode 270, the Mikes and Tina and James stay viral, and discuss the best available evidence around the use of antiviral medications for treatment of the flu. At the end, we all agree there is an effect and that the person who should make the decision should be the patient once they have had the benefits and harms appropriately explained. Read more »

Episode 269: The ins and outs of the HPV vaccine

In episode 269, the Mikes and James go viral on the HPV vaccine. We discuss what the evidence shows around the use of the HPV vaccine in females and males and in contrast to many people, we actually present the numbers so that you can help people, or help yourself make decisions.

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Episode 268: An agitating podcast on benzo’s for agitation in dementia

In episode 268, Mike and James discuss the use of benzodiazepines in the management of agitation in demented elders. We discuss the evidence and realise that the evidence is at best iffy. Nonetheless, they seem to be as effective as antipsychotics but both classes of drugs have side effects and should be used in low doses and stopped as soon as possible.  Read more »

Episode 267: PREMIUM – Guidelines, blood pressure and antiplatelets

In episode 267, James and Mike finally get to the first PREMIUM podcast of 2015 – and boy is it something. We discuss a new paper put out by the Edmonton gang on who actually contributes to primary care guidelines, we talk about a new systematic review of mild hypertension treatment, and finally discuss a NEJM article on the duration of dual antiplatelets. Read more »

Episode 266: Questions, questions, questions PART IV

In episode 266, James and Mike finally get to the end of listener questions. We talk about NSAIDs and inflammation, cognitive impairment and statins, dosing of antibiotics, antidepressants and efficacy, and antiplatelets and ethnicity. We give answers which either clarify or confuse the issues.

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