Episode 94: More questions posed, and more answers composed - Benzos, serotonin syndrome, big pressures and low doses

In episode 94, we get to yet more listener questions and provide vague, yet deep and thoughtful answers. We talk about the use of benzodiazepines, serotonin syndrome, buspirone, 'urgent' hypertension and pontificate even more on low doses.

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Comments

Doc Rock, I agree entirely.

Doc Rock, I agree entirely. I think the study you are referring to is Hayward's group and though it is a model, it is logical, simple and allows us to reduce the treatment of lipids to what they should be: simple. That would allow more time for discussion with patients and for more patients, and would help reduce the anxiety that patients often have about lipids...iatrogenic anxiety, I think.
Mark

I'm pretty sure that it was

I'm pretty sure that it was this podcast with the question about statin doses... There is a study in Annals of Internal Medicine in January 2010 about statins for primary prevention. It's a model study, so based on assumptions, but the doses of statins they used are 40 of simvastatin vs. 40 of atorvastatin. It uses the idea of treating based on CAD risk and not on LDL. I imagine this could be a reason to use Simvastatin 40mg rather than 20mg.

It's a nice study because it suggests how we can make things simple. I'm not sure why we try to make medicine so complicated.

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