Episode 114: Topical information on topical NSAIDs

Submitted by JPM on Tue, 2011-02-01 14:08

In episode 114, James and Mike finally bring some topical information to the TEC podcast listeners by reviewing the available evidence for topical NSAIDs. We find out that they do work and that they should be considered a useful tool in your "how should I treat pain" armamentarium.

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Comments

dare I say....pharmacokinetics?!

Submitted by Jan on Fri, 2011-02-11 10:38.

I've heard that the absorption of topical NSAIDs can depend on how thin or fat the patient is. Is this true, and which causes the better result? Does the fat act like a depot and give more sustained action, or is there better absorption in a thinner patient/joint closer to the skin, or is all this just myth/conjecture?!

PLO gel

Submitted by Anonymous on Thu, 2011-02-24 21:42.

PLO stands for pluronic lecithin organogel. The lipid layer in the PLO gel enhances penetration across all skin layers. You could have asked a compounding pharmacist to join the podcast for this one. =)

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