high blood pressure


Episode 295: PREMIUM - Taking a run at the SPRINT trial

In episode 295, Mike and James discuss the latest blood pressure target trial in an impressive PREMIUM way. We also discuss the most recent meta-analysis that looked at all of the studies (except SPRINT) that have evaluated intensive blood pressure lowering. Read more »

Episode 283: PREMIUM – Glucose, blood pressure and statin studies to the max

In episode 283, Mike and James discuss the latest T2DM study showing that sitagliptin at least doesn’t cause much harm. We then veer off to discuss everything you need to know about diastolic and systolic blood pressure and how are they associated with CVD. Finally we discuss an n-of-1 study looking at statin-related myalgia. Bottom line – this was clearly a PREMIUM podcast. Read more »

Episode 228: PREMIUM – The new JNC8 high blood pressure guidelines dissected and exposed

In episode 228, Mike and James deconstruct the most recent JNC 8 high blood pressure guidelines. We discuss what is good and bad and we debate the issues and what the changes might mean for practice. Read more »

Episode 207: Please stop measuring all those blood pressures – PART II

In episode 207, Mike and James keep up the pressure on blood pressure measurements. We talk about the magnitude of the benefit, the variability of all these measurements and get into the whole starting and stopping approach. At the end of the podcast we decide the bottom line is to not panic, sit back, put up your feet and relax and try to get your patients to do the same thing. Read more »

Episode 206: Please stop measuring all those blood pressures

In episode 206, James and Mike start to tackle the holy gospel of blood pressure measurements and interestingly feel under pressure the entire way due to the trickiness of the evidence. Read more »

Episode 158: You say chlorthalidone I say hydrochlorothiazide

In episode 158, Mike and James work under very distressing conditions (no microphones, colds, Bubonic plague) and discuss the issue of which thiazide should you choose. Evidence, personal experience and values swirl continually through the diatribe. Read more »

Episode 102: Blood pressure targets: Bullseye or Bulls--t

In episode 102, Mike and James, with laser precision, look at the evidence around blood pressure targets. We cover data in non-diabetics, diabetics, chronic kidney disease and the elderly. At the end they agree that the BP target we used 30 years ago (140/90) is still pretty good. Read more »

Episode 94: More questions posed, and more answers composed - Benzos, serotonin syndrome, big pressures and low doses

In episode 94, we get to yet more listener questions and provide vague, yet deep and thoughtful answers. We talk about the use of benzodiazepines, serotonin syndrome, buspirone, 'urgent' hypertension and pontificate even more on low doses. Read more »

Drugectomies - DTC 2010

This week we have something slightly different for you. Read more »

Episode 77: The frail elderly - blood pressure is good - Part II

In episode 77, Mike and James stop waxing philosophically and get specific about therapeutics and the frail elderly. Once again we get our friend and colleague John Sloan to help us navigate through this evidence-free zone. We specifically talk about how to deal with the patient on 47 drugs and what to do about blood pressure, cholesterol, osteoporosis, and type 2 diabetes. Read more »

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