dabigatran

dabigatran

Episode 180: A RELYable ARISTOTELian look at ROCKET science

In episode 180, Mike and James invite Mike Kolber back to go over the three major trials that have compared warfarin to the new oral anticoagulants. We try, with limited success, to put all the science into perspective. At the end of the podcast, against all odds, we each have a stroke and a major bleed at the same time which dampens our recommendations.

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Episode 126: Questions from near and far and answers from way out - Part II

In episode 126, James and Mike discuss how to do a drugectomy and why one needs to consider evidence, efficacy, side effects, cost, patient preference and that as clinicians we need to do many "n of 1" trials. We then discuss the concerns around dabigatran and what to do about bleeding on this agent and why the FDA made the 150 mg dose the chosen one. Read more »

Episode 118: The mind boggles and the heart goes all a flutter - Part 2

In episode 118, James and Mike continue their discussion of atrial fibrillation by going into details about the evidence for treating patients with atrial fibrillation and how to make decisions between ASA/warfarin/dabigatran and also what it means to be in or out of the INR therapeutic range. Read more »

Episode 117: The mind boggles and the heart goes all a flutter

In episode 117, Mike and James delve into the first of a few podcasts on options for atrial fibrillation. In this first podcast they look at ways to assess risks and talk at length about a web-based tool that makes the process as easy as possible. The process is so easy that the hearts of both Mike and James start to flutter yet only one of them decides to take warfarin. Read more »

Episode 112: Dabigatran versus Warfarin, James versus Mike, Right versus Wrong

In episode 112, Mike and James discuss the who, what, why, where and when of dabigatran in atrial fibrillation. We look at the data, and then discuss what we as individuals would do when making a decision between dabigatran and warfarin. At the end we both agree to disagree with the fact that we agree to disagree.

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Episode 68: The "heart of the matter" for stroke prevention in atrial fibrillation

In episode 68, we get to the “heart of the matter” of stroke prevention for atrial fibrillation. We find out from Peter Loewen, that it is all a numbers game, and he gives us the tools to deal with this issue. We talk about warfarin and ASA and clopidogrel with respect to their benefits and harms. Read more »

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